Travel by car: the driving distance between Amsterdam and Mostar 1830 km which equals a travelling time of approximately 17 hours under normal circumstances. This route has toll fees except for Germany where the highway is free of charge.
Travel by bus: Timetable and price tickets for direct buses from Amsterdam to Mostar, if any, you can check here.
Alternative ways of travelling from Amsterdam to Mostar:
Travel by train: it is possible to travel by train on this route with changing trains in Munich and then Zagreb to Sarajevo. From Sarajevo there is direct train to Mostar. More informations about trains in Bosnia and Herzegovina you can check here.
Travel by plane: there is no direct flight on this route. It is possible to travel via Sarajevo airport but also with stopovers.
Map with buses from Mostar: